This article presents an integrative framework for designing resilient, automated monitoring and fault-tolerant control systems for critical building infrastructure, with an emphasis on heating, ventilation, and air-conditioning (HVAC) systems. The proposed framework synthesizes advances in GPU-accelerated anomaly detection, infrastructure-as-code (IaC) for reproducible deployment, self-correcting control strategies, and organizational preparedness in emergency scenarios. The study draws on interdisciplinary evidence spanning disaster and emergency planning, GPU concurrency and diagnostic automation, advanced anomaly detection in large sensor networks, automated deployment methods, and domain-specific best practices for HVAC control and fault detection. The framework is organized into four interlocking pillars: (1) high-throughput real-time anomaly detection using graph and spatio-temporal models accelerated on commodity GPUs, (2) deterministic, auditable deployment and lifecycle management of monitoring pipelines through IaC, (3) model-based self-correcting controls and fault-tolerant supervisory strategies aligned to ASHRAE standards, and (4) organizational preparedness and recovery planning to close the loop between technical detection, operational response, and disaster resilience. Methodological exposition details the system architecture, data handling, algorithmic choices, and software lifecycle practices; a descriptive results section synthesizes expected outcomes and system behavior under a range of fault modes; and an extended discussion elaborates theoretical implications, limitations, and a pathway for future research and deployment. The design emphasizes safety, reproducibility, and operational viability: detection precision and recall are framed alongside latencies achievable by GPU acceleration and the governance benefits afforded by IaC. The conclusions highlight how coordinated technical and organizational practices can materially improve the readiness, response, and recovery of building systems facing sensor faults, actuator failures, or anomalous dynamics during emergencies. This research contributes a pragmatic, integrative roadmap for researchers, facility engineers, and system integrators seeking to move beyond isolated algorithms toward production-ready resilience for critical built-environment infrastructure.