Ischemic priapism is a prolonged, painful erection that can lead to significant morbidity if not promptly treated. While various etiologies have been identified, the occurrence of ischemic priapism as a result of alpha blocker therapy is exceedingly rare. This report presents the case of a 45-year-old male with a history of benign prostatic hyperplasia who developed ischemic priapism following the initiation of alpha blocker medication. The patient experienced an erection lasting over four hours, accompanied by severe pain and discomfort. Upon presentation to the emergency department, a thorough evaluation confirmed the diagnosis of ischemic priapism, and the patient was promptly treated with aspiration and irrigation of the corpus cavernosum. Follow-up assessments revealed a successful resolution of symptoms and restoration of erectile function.

This case highlights the importance of recognizing alpha blockers as a potential cause of ischemic priapism, even in the absence of prior reports linking the two. It underscores the necessity for healthcare providers to be vigilant in monitoring patients receiving alpha blocker therapy for signs of priapism. Furthermore, this case adds to the limited literature on drug-induced ischemic priapism and emphasizes the need for further investigation into the underlying mechanisms and management strategies associated with this rare condition.

Subungual glomus tumors are rare, benign neoplasms arising from the glomus body, typically located beneath the nail bed. They are characterized by distinct clinical features, including localized pain, tenderness, and a bluish discoloration of the nail, which can significantly impact a patient's quality of life.

This study aims to examine the clinical presentation, diagnosis, surgical management, and outcomes of patients with subungual glomus tumors. A retrospective analysis was conducted on patients diagnosed with subungual glomus tumors at our institution over a five-year period. Clinical data, including demographics, symptom duration, physical examination findings, imaging studies, surgical techniques, and postoperative outcomes, were collected and analyzed.

A total of 15 patients with histologically confirmed subungual glomus tumors were included in the study. The mean age at presentation was 35 years, with a higher prevalence in females. The most common presenting symptoms were severe localized pain and tenderness, often exacerbated by cold temperatures. Imaging studies, including ultrasound and MRI, were utilized to aid in diagnosis, although the definitive diagnosis was made through excisional biopsy. Surgical excision was performed in all cases, with a mean follow-up of 12 months. Postoperatively, most patients reported significant pain relief and satisfactory cosmetic outcomes. Recurrence was noted in two patients, necessitating re-excision.

Subungual glomus tumors, though rare, should be considered in patients presenting with localized nail pain and tenderness. Early diagnosis and surgical excision are crucial for effective management and optimal outcomes. This study highlights the importance of a multidisciplinary approach, including clinical examination and imaging, in the timely identification and management of these tumors. Further research is warranted to explore long-term outcomes and recurrence rates associated with different surgical techniques.